产品货号:
Z11607
中文名称:
ATG3抗体
英文名称:
Anti-ATG3 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ATG3 Antibody |
指标别名 | APG3;APG3 LIKE;APG3L;ATG3;Autophagy related protein 3;hApg3;PC3 96;Protein PC3 96 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | ATG3 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | ATG3 antibody was raised against an 18 amino acid synthetic peptide near the center of human ATG3.The immunogen is located within amino acids 180 - 230 of ATG3. |
计算分子量 | 36kDa |
成分 | ATG3 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | ATG3 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Autophagy,the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells.It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components.This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1.ATG3 (APG3) is a widely expressed conjugating enzyme for APG8 lipidation,an essential step for the initiation of autophagy.It functions as an E2-like enzyme during the initial stages of autophagosome formation by catalyzing the formation of the Atg8-phosphatidylethanolamine (Atg8-PE) conjugate,which is critical for autophagy. |
Uniprot ID | Q9NT62 |
基因名全称 | ATG3 autophagy related 3 homolog (S.cerevisiae) |
蛋白名全称 | ATG3 autophagy related 3 homolog (S.cerevisiae) |
推荐稀释比 | ATG3 antibody can be used for detection of ATG3 by Western blot at 1 ~ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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